This page lists notable recent links and posts from Systematic I.S. Strategies Ltd. and industry colleagues.

MES solution-agnostic industry templates for Pharma 4.0

MES is a foundational digital manufacturing technology in Life Sciences. It is an enabler for Pharma 4.0. Despite its industry maturity, MES adaption is still generally burdensome in terms of cost, risk, disruption, and meeting overall stakeholder expectations.

The “MES Industry Templates” working group within the ISPE GAMP MES SIG develops solution-agnostic, manufacturing modality specific, MES functional templates to fast-track & risk-reduce MES rollouts, expediting the overall Pharma 4.0 journey

PHARMACEUTICAL ENGINEERING, iSpeak Blog 29 February 2024

Manufacturing Execution Systems (MES): Beyond ROI, a New Look at Business Payback

By Eddie Ryan, Systematic I.S. Strategies Ltd

Older posts of interest ..

 

Systematic Takeda Ebrs Case Studyv 1 600 Dpi Pdf
PDF – 661.9 KB 57 downloads
Sysiss Brochure Legacy 2010 A 72 Dpi Pdf
PDF – 469.8 KB 64 downloads

Digital Transformation in Biopharmaceutical Manufacturing, a pragmatic perspective

 

Eddie Ryan, Guest Speaker

 

Lecture Series: Quality Management in a Digital Age

Level 9 (Postgraduate Diploma) Digital Transformation Class

Griffith College / Innopharma Education, April 2022

Posted August 2025

Best In Class Integrated Pharmaceutical Manufacturing, a perspective from 17 years ago

 

Systematic I.S. Strategies Ltd. visualization of integrated enterprise and plant systems. The graphic, developed in 2008 (!!!), shows system technical & functional complexity versus the level of typical deployment localization.

An interesting perspective considering the current (2025) push for functional simplification, faster deployments, fully integrated digital eco-systems, and a drive for a full range of globally hosted digital manufacturing systems, ideally Cloud based SaaS. Alas, we're not there yet...

  • MES = Manufacturing Execution System

  • EBRS = Electronic Batch Record System

  • LIMS = Labratory Information Management System

  • ELN = Electronic Laboratory Notebook

  • CDS = Chromatography Data System (or Network Data System)

  • SCADA = Supervisory Control And Data Acquisition

  • DCS = Distributed Control System

  • EAM = Enterprise Asset Management

  • CMS = Calibration Management System

  • FMS = Facilities Management System

  • ECMS = Electronic Content Management System

  • EDMS = Electronic Document Management System

  • EQMS = Electronic Quality Management System

  • HCM = Human Capital Management (System)

  • LMS = Learning Management System

  • L&D = Learning & Development (System)

  • PPS = Production Planning System

  • Talent Mgt = Talent Management (System)

  • WMS = Warehouse Management System

  • MRP = Material Requirements Planning

  • ERP = Enterprise Resource Planning

  • Bench = lab bench-top equipment proprietary software & firmware